﴿ مَآ أَنتَ بِنِعْمَةِ رَبِّكَ بِمَجْنُونٍۢ ﴾

“Thou art not, by thy Sustainer's grace, a madman!”

You are not O Muhammad (s) by the grace of your Lord a madman that is to say madness is precluded in your case on account of your Lord’s grace to you by way of His assigning to you prophethood and in other ways — this was a refutation of their saying that he was a madman.