﴿ إِنَّ ٱلَّذِينَ يُحَآدُّونَ ٱللَّهَ وَرَسُولَهُۥٓ أُو۟لَٰٓئِكَ فِى ٱلْأَذَلِّينَ ﴾

“Verily, those who contend against God and His Apostle - it is they who [on Judgment Day] shall find themselves among the most abject.”

(Lo! those who oppose) contravene (Allah and His messenger) in the matter of religion, (they will be among the lowest) in the Fire. The reference here is to the Jews and hypocrites.