﴿ فَلَا تُطِعِ ٱلْمُكَذِّبِينَ ﴾

“Hence, defer not to [the likes and dislikes of] those who give the lie to the truth:”

(Therefore obey not thou) O Muhammad (the rejecters) the disbelievers in Allah, His Scripture and His Messenger, i.e. the leaders of the people of Mecca